abstract：:Only about 8% of head and neck tumors affect the midface. This anatomical area is characterized by an enormous number of functionally important structures, and it is frequently only possible to achieve small resection margin distances. To avoid complications and unfavorable results, a dedicated preparation of both pat...

journal_title：HNO

authors： Beule AG

更新日期：2018-06-01 00:00:00

abstract：:As immunotherapy is becoming increasingly important in the treatment of head and neck cancer, a fundamental understanding of the immunological relationships in the tumor microenvironment is required. The importance of tumor-infiltrating B cells (TIL-B) has been largely neglected so far. In the current literature, howe...

journal_title：HNO

authors： Schuler PJ,Brunner C,Hoffmann TK

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Superior canal dehiscence syndrome (SCDS) is a relatively rare neurotological disorder that is characterized by a heterogeneous clinical picture. Recently, vestibular evoked myogenic potential (VEMP) measurement was established for the diagnosis of SCDS. In the present study, a case series of patients with S...

journal_title：HNO

authors： Gürkov R,Jerin C,Flatz W,Maxwell R

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Vestibular schwannoma (VS) is a benign tumor that develops in the internal auditory canal and the cerebellopontine angle, potentially diminishing hearing or balance. Most VS tumors arise from one of two vestibular branches: the superior or inferior vestibular nerve. Determining the specific nerve of origin c...

journal_title：HNO

authors： Rahne T,Plößl S,Plontke SK,Strauss C

更新日期：2017-12-01 00:00:00

abstract：:In Germany high-resolution sonography using the color duplex mode in addition to computed tomography (CT) is a well-established and proven method in the context of restaging after primary therapy of head and neck squamous cell cancer (HNSCC). There are no international evidence-based restaging guidelines. Decisions co...

journal_title：HNO

authors： Künzel J,Bozzato A,Strieth S

更新日期：2017-11-01 00:00:00

abstract：:The current paper reports on a patient with recurrent rotational vertigo and persistent dizziness and imbalance lasting weeks, who underwent extensive neurootological and radiological examination. Pathological findings initially included right-sided benign paroxysmal positional vertigo (BPPV), persistent horizontal sp...

journal_title：HNO

authors： Volgger V,Gürkov R

更新日期：2017-11-01 00:00:00

abstract：:During recent decades, the clinical use of botulinum toxin has become increasingly well established. In the field of otorhinolaryngology there are many indications for which botulinum toxin can improve patients' quality of life. These include applications in the region of the head and neck muscles and the autonomic ne...

journal_title：HNO

authors： Laskawi R,Olthoff A

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The prognostic potential of click-evoked early acoustic evoked potentials (EAEP) for vestibular schwannoma (VS) diagnostics is considered insufficient for tumors small than approximately <1.5 cm in diameter. However, up until now, the derivations at higher sound pressure levels have mainly been used for EAEP...

journal_title：HNO

authors： Baljić I,Börner-Lünser E,Eßer D,Guntinas-Lichius O

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Except for glucocorticoids there is a lack of neuroprotective medication in neurosurgical interventions. OBJECTIVE:An overview of clinical trials investigating administration of the calcium antagonist nimodipine and hydroxyethyl starch (HES) in vestibular schwannoma (VS) surgery is given. Basic research is ...

journal_title：HNO

authors： Scheller C,Herzfeld E,Strauss C

更新日期：2017-09-01 00:00:00

abstract：:The current paper reports on a patient with recurrent rotational vertigo and persistent dizziness and imbalance lasting several weeks, who underwent extensive neuro-otological and radiological examinations. Pathological findings initially included right-sided benign paroxysmal positional vertigo (BPPV), persistent hor...

journal_title：HNO

authors： Volgger V,Gürkov R

更新日期：2017-08-01 00:00:00

abstract：:This article presents the case of an IgG4-related disease in a patient with clinical signs of a malignant tumor of the oral cavity. After excluding the suspicion of a malignant lesion, vasculitis and various infectious diseases were ruled out. Finally, due to further immunohistochemical studies, IgG4-related disease w...

journal_title：HNO

authors： Engelbarts M,Schad A,Matthias C

更新日期：2017-08-01 00:00:00

abstract：:Classic gastroenterological diagnostic tools have proven to be insufficient in identifying the causal relationship between extra-esophageal symptoms and presumed pathological reflux activity. Some new methodological approaches, such as functional endoscopy (video panendoscopy, VPE), are considered to be helpful. Howev...

journal_title：HNO

authors： Michel F,Stroh T,Fritsche R,Ahrens P

更新日期：2017-08-01 00:00:00

abstract：:Millions of people worldwide suffer from hearing loss. Current treatment for patients with severe to profound hearing loss consists of cochlear implants. Providing the cochlear nerve is intact, patients generally benefit enormously from this intervention, frequently achieving significant improvements in speech compreh...

journal_title：HNO

authors： Roemer A,Staecker H,Sasse S,Lenarz T,Warnecke A

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Positional obstructive sleep apnea (POSA) is common in mild and moderate forms of obstructive sleep apnea (OSA). Two smartphone applications (apps) professing to avoid the supine position (SP) are available: for Android the "Apnea Sleep Position Trainer" and for iOS the "SomnoPose-Sleep Position Monitor". Th...

journal_title：HNO

authors： Haas D,Birk R,Maurer JT,Hörmann K,Stuck BA,Sommer JU

更新日期：2017-02-01 00:00:00

abstract：:Wullstein, the founder of modern microscopic ear surgery, already used an oto-endoscope intraoperatively. However, it is only after the recent development of modern video-endoscopy with high-definition, 4K, and 3‑dimensional imaging that endoscopically guided surgery of the middle ear is gaining some importance. Key v...

journal_title：HNO

authors： Preyer S

更新日期：2017-01-01 00:00:00

abstract：:The various stages of tumor growth are characterized by typical epithelial, vascular, and secondary connective tissue changes. Narrow Band Imaging (NBI) endoscopy is a minimally invasive imaging technique that presents vascular structures in particular at a higher contrast than white light endoscopy alone. In combinat...

journal_title：HNO

authors： Arens C,Betz C,Kraft M,Voigt-Zimmermann S

更新日期：2017-01-01 00:00:00

abstract：:Intraoperative magnetic resonance imaging is a widely accepted method for resection control of glial tumors. Increasingly, it is also used during the resection of skull base tumors. Several studies have independently demonstrated an increase in the extent of resection in these tumors with improved prognosis for the pa...

journal_title：HNO

authors： Hlavac M,Wirtz CR,Halatsch ME

更新日期：2017-01-01 00:00:00

abstract：:Over the past few years, the diagnostic tools and therapeutic approaches for obstructive sleep apnea (OSA) have evolved further. Based on a review of the current literature and the personal experiences of the authors, the most relevant developments are summarized in this article and discussed with regard to their impa...

journal_title：HNO

authors： Stuck BA,Maurer JT

更新日期：2017-01-01 00:00:00

abstract：:Due to the increasing incidence of hymenoptera venom allergies and the potentially life-threatening reactions, it is important for otolaryngologists working in allergology to have an understanding of modern diagnostic and treatment standards for this allergic disease. Molecular diagnosis with recombinant single allerg...

journal_title：HNO

authors： Klimek L,Dippold N,Sperl A

更新日期：2016-12-01 00:00:00

abstract：:Local drug application to the inner ear offers a number of advantages over systemic delivery. Local drug therapy currently encompasses extracochlear administration (intratympanic injection); intracochlear administration, particularly for gene and stem cell therapy; as well as various combinations with auditory neurose...

journal_title：HNO

authors： Plontke SK,Götze G,Rahne T,Liebau A

更新日期：2016-11-01 00:00:00

abstract：:Georg Schlöndorff (1931-2011) developed the idea of computer-assisted surgery (CAS) during his time as professor and chairman of the Department of Otorhinolaryngology at the Medical Faculty of the University of Aachen, Germany. In close cooperation with engineers and physicists, he succeeded in translating this concep...

journal_title：HNO

authors： Mösges R

更新日期：2016-09-01 00:00:00

abstract：:The Freiburg speech intelligibility test according to DIN 45621 was introduced around 60 years ago. For decades, and still today, the Freiburg test has been a standard whose relevance extends far beyond pure audiometry. It is used primarily to determine the speech perception threshold (based on two-digit numbers) and ...

journal_title：HNO

authors： Hoth S

更新日期：2016-08-01 00:00:00

abstract：:Human papilloma viruses (HPV) are responsible for approximately half of all oropharyngeal squamous cell carcinomas (OPSCC) and incidence rates of HPV-associated OPSCC continue to increase substantially. The defined viral carcinogenesis permits development of specific diagnostic, therapeutic, and prophylactic approache...

journal_title：HNO

authors： Reuschenbach M,Wagner S,Würdemann N,Sharma SJ,Prigge ES,Sauer M,Wittig A,Wittekindt C,von Knebel Doeberitz M,Klussmann JP

更新日期：2016-07-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is characterized by its intense immune suppression and its elaborate immune escape mechanisms. Due to the fact that survival rates remain low, the role of immunotherapy has become more important and the focus of current clinical studies has shifted toward antibody-based im...

journal_title：HNO

authors： Schuler PJ,Doescher JC,Laban S,Hoffmann TK

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Autologous transplants comprising skin and cartilage, so-called composite grafts (cgs), are an important reconstructive tool for multilayered defects of the nose. A cg from the auricular cavum conchae needs to fulfill both functional and esthetic demands. OBJECTIVE:This article illustrates the indications f...

journal_title：HNO

authors： Nordmann M,Veit J,Rotter N,Hoffmann TK,Scheithauer MO

更新日期：2016-05-01 00:00:00

abstract：:Specific anosmia, the inability to perceive a specific odor, while olfactory perception is otherwise intact, is known as a rather seldom phenomenon. By testing the prevalence of specific anosmia to 20 different odors in a sample of 1600 people, we were able to estimate the general prevalence of anosmia. This revealed ...

journal_title：HNO

authors： Croy I,Olgun S,Mueller L,Schmidt A,Muench M,Gisselmann G,Hatt H,Hummel T

更新日期：2016-05-01 00:00:00

abstract：:Despite recent advances in radiochemotherapy, treatment of locally advanced head and neck squamous cell carcinoma is still challenging, and survival rates have improved only slightly. This is due to the high frequency of metastases and local and/or regional tumor recurrences that have acquired radio- or chemoresistanc...

journal_title：HNO

authors： Heß AK,Weichert W,Budach V,Tinhofer I

更新日期：2016-05-01 00:00:00

abstract：:Headache is the main symptom in a wide variety of diseases of which ear, nose and throat (ENT) entities are only a small fraction but are not reflected in the number of patients. Comprehensive knowledge of the clinical signs of the most common primary headaches, e. g. migraine, is therefore essential for the ENT speci...

journal_title：HNO

authors： Michel O

更新日期：2016-01-01 00:00:00

abstract：:In cystic fibrosis (CF) mucociliary clearance of the entire respiratory system is impaired. This allows pathogens, such as Pseudomonas aeruginosa to persist and proliferate, which by progressive pulmonary destruction causes 90 % of premature deaths due to this inherited disease. The dramatic improvement in life expect...

journal_title：HNO

authors： Mainz JG,Gerber A,Arnold C,Baumann J,Baumann I,Koitschev A

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The role of transoral robotic surgery (TORS) in the treatment of head and neck tumors has expanded in the last decade. OBJECTIVES:We present the development and current advances in TORS along with the current indications and contraindications, and describe future developments. METHODS:We present our own st...

journal_title：HNO

authors： Mattheis S,Kansy B,Haßkamp P,Holtmann L,Lang S

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Transoral laser microsurgery (TLM) is the method of choice for partial laryngectomy in Germany. In advanced stages, chemoradiotherapy is increasingly indicated for organ preservation. OBJECTIVE:This report considers the indications for and outcomes of supracricoid partial laryngectomy (SPL), also known as c...

journal_title：HNO

authors： Schroeder U,Wollenberg B,Bruchhage KL

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Balloon dilation of the Eustachian tube has recently been introduced as a novel and minimally invasive method for treating chronic obstructive Eustachian tube dysfunction. For the first time worldwide, we assessed the role of this technique in a large cohort of children with Eustachian tube dysfunction that d...

journal_title：HNO

authors： Maier S,Tisch M,Maier H

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Balloon Eustachian Tuboplasty (BET) is a new minimally invasive treatment for chronic Eustachian tube dysfunction (ETD). Initially, perioperative prophylactic antibiotic therapy with ciprofloxacin 2 × 500 mg p.o. for 5 days was administered. This study aimed to characterize the bacterial flora in the ET, nos...

journal_title：HNO

authors： Schröder S,Abdel-Aziz T,Lehmann M,Ebmeyer J,Sudhoff H

更新日期：2015-09-01 00:00:00

abstract：:This year also saw a great number of phase II and III studies presented at the ASCO Annual Meeting, in which new drugs (monoclonal antibodies, small molecules) were investigated as an alternative to or in combination with established mono- and polychemotherapy in patients with recurrences or distance metastases from h...

journal_title：HNO

authors： Bußmann L,Busch CJ,Knecht R

更新日期：2015-09-01 00:00:00

abstract：AIM:The influence of bilateral cochlear implants (CI) and unilateral CI on the self-reported listening effort in standardized situations is being assessed. SAMPLE AND METHODS:The sample consisted of 34 bilateral and 38 unilateral adult CI users. Unilateral CI users had at least severe hearing loss in the non-implanted...

journal_title：HNO

authors： Schnabl J,Bumann B,Rehbein M,Müller O,Seidler H,Wolf-Magele A,Sprinzl G,Windfuhr J,Weichbold V

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:To allow passage of food, the swallowing process closes off the larynx and interrupts respiratory flow. Both the timing of the interruption of respiratory flow and the body position can affect the results of the swallowing process. OBJECTIVE:The effect of body position on the swallowing process and the coor...

journal_title：HNO

authors： Schultheiss C,Wolter S,Schauer T,Nahrstaedt H,Seidl RO

更新日期：2015-06-01 00:00:00

abstract：:The APD guideline of 2009 was supplemented by the statements listed here. The addition is based on current knowledge and findings. Otherwise, the Guideline 2009 remains valid. Here, a summary of the updated APD guideline is given, thus proving an overview of the definition of APD, diagnosis, differential diagnosis and...

journal_title：HNO

authors： Nickisch A,Gross M,Schönweiler R,Berger R,Wiesner T,Am Zehnhoff Dinnesen A,Ptok M

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:Hearing aids (HA) provide adequate support for many patients with hearing loss, but not all. Around one third of 10.000 patients provided with hearing aids in the Abbreviated Profile of Hearing Aid Benefit felt no actual benefit when using the hearing aid, although they demonstrated the necessary hearing i...

journal_title：HNO

authors： Braun K,Zenner HP,Friese N,Tropitzsch A

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Allergic diseases are among the most common diseases of humans. The immune response towards allergens is regulated by T-lymphozytes and characterized by an interleukin (IL)-4, IL-5 and IL-13 dominated Th2 cytokine profile. RESULTS:Allergen-specific immunotherapy (AIT) is the only causative treatment option ...

journal_title：HNO

authors： Klimek L,Kündig T,Senti G

更新日期：2015-05-01 00:00:00

abstract：:Tinnitus can be caused or triggered by functional disorders of the cervical spine, temporomandibular joint or any other musculoskeletal structure of the neck or head. This special form of tinnitus is called somatosensory tinnitus and represents a discrete subgroup among the different kinds of tinnitus. Distinctive for...

journal_title：HNO

authors： Biesinger E,Groth A,Höing R,Hölzl M

更新日期：2015-04-01 00:00:00